Endocrine Abstracts

Purpose: The aim of this study was to evaluate the effects of methomyl 25%WP (Lannate, carbamate broad spectrum insecticide) on the reproductive parameters in female Wistar rats during pregnancy and the possible protective role of vitamin E against methomyl-induced toxicity.Methods: The animals were randomly divided into four groups, eight of each. Group I served as control; Group II received orally a dose of methomyl (Met, 10 mg/kg per day), Group III w...

Selective serotonin reuptake inhibitors (SSRI) are a class of molecules used in treating depression, anxiety, and mood disorders. Paroxetine (PRT) is one of the mostly prescribed antidepressant which has attracted great attention regarding its side effects in recent years. This study was planned to assess the adverse effects of paroxitine on the biochemical parameters and reproductive system. Fourteen male wistar rats were randomly allocated into two groups (7...

In this study, we attempted to assess the toxicity of Methyl Thiophanate (MT) on the biochemical and reproductive parameters in male Wistar rats as well as the possible protective role of Zingiber officinale (Ginger, Ging) extract against MT-induced toxicity. Hence, forty adult Wistar rats were allocated into four groups of 10 rats for each; the first group served as control, groups 2, 3 and 4 were treated orally (5/week) for 8 weeks by MT (150 mg/kg bw), Ging (100 mg...

Methomyl (MET) is a carbamate insecticide used worldwide to protect a wide variety of crops from insect nuisances. Besides this beneficial role, it is classified as highly toxic compound for humans and animals by the EPA. Pistacia Lentiscus (PL) is a shrub that grows in the Mediterranean region; plant parts and oil have a long history in folk medicine in healing several diseases by their antioxidant, anti-inflammatory, antimicrobial, antifungal, antiatherogenic and anticancer ...

Synapses are the key elements for signal transduction and plasticity in the brain. Despite a relatively large number of assumptions that have been made on the structure of mature cortical synapses in many other animal species, little is known about these structures in human. Hence, synapses in cortical layer 5 (L5), the main recipient layer of thalamocortical efferents, which representing the first station of cortical information processing were investigated structurally and q...

Nicotine (N) is known as the main toxic and addictive component of cigarette smoke. By its ability to generate reactive oxygen species (ROS) and oxidative damage in organism, it can induce major public health problems such as cancer, cardiovascular diseases and infertility. Green tea extract (GTE) is an important source of polyphenols catechins; it has attracted a great deal of attention around the world because of its potential antioxidants role in scavenging free radicals. T...

Lambda-cyhalothrin is a potent synthetic type II pyrethnoid used worldwide to control a wide range of insects in agriculture, forestry, human health, and home. The purpose of this study is to investigate the effects may occur on hematological and testicular functions by this pesticide. Two groups of wistar rats were used, the first group served as control and the second experimental was received an emulsion solution of Lambda-cyhalothrin by orale route at dose of 23 mg/kg duri...

The present study was carried out to investigate the possible toxic effects of different doses of a two component of Nurelle D 220 EC (200 g of chlorpyriphos-ethyl and 20 g cypermethrin per 1 l) on blood hematology, testosterone and thyroxin levels, and semen quality of male rats. As well as histological examination of testis and epididymis. The investigation covered four groups of 8 rats each: three experimental groups and one served as control. The mixture liquid was given t...